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Beware of NK cells in pre-clinical metastasis models

L A Coupland1, B H Chong, C R Parish

  • 1Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, Australia.

Clinical & Experimental Metastasis
|April 23, 2013
PubMed
Abstract

No abstract available in PubMed .

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Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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