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Complexation of the mycotoxin zearalenone with β-cyclodextrin: Study of the interaction and first promising
C Dall'asta1, A Faccini, G Galaverna
1Department of Industrial and Organic Chemistry, University of Parma, Viale G.P. Usberti 17/A, 43100, Parma, Italy, chiara.dallasta@unipr.it.
Abstract:
This work reports the study of the interactions between native and substituted β-cyclodextrins and zearalenone and its derivatives α- and β-zearelonol. The data obtained by fluorescence and NMR experiments suggested that zearalenone, α- and β-zearalenol and cyclodextrins give rise to host-guest complexation, with the inclusion of the phenolic moiety inside the cyclodextrin cavity. The high stability of these complexes induces a high fluorescence enhancement upon complexation. These results have been successfully applied to the spectrofluorimetric determination of zearalenone in maize raw samples, without any chromatographic separation.
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