[The bile-diverting methods in long-term obstructive jaundice]

There were examined 59 patients, admitted to hospital for residual choledocholithiasis, complicated by durable (during more than 2 weeks) obturation jaundice, who were treated in 2009-2012 yrs. In 37 patients (the first group) endoscopic papillosphincterotomy was conducted and choledocholithoextraction, in 22 (the second group)--after endoscopic papillosphincterotomy and choledocholithoextraction nasobiliary drainage was performed during 3-8 days. Besides the conventional clinical and instrumental investigations, there were examined also the spectrum of conjugated and nonconjugated biliary acids in the blood plasm, as the indices of the bile toxicity and early markers of hepatic insufficiency occurrence. There was established in the blood serum of both groups of patients the content increase of the biliary acids toxic fractions. In the patients of the second group the toxic fractions of biliary acids disappearance was observed trustworthy earlier, than in patients of the first group.