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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Targeting melanoma by small molecules: challenges ahead
1Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Pigment Cell & Melanoma Research
|April 25, 2013
Abstract:
Significant progress has been made in targeting melanoma using small molecule inhibitors, but challenges remain. Here we describe the history of screening approaches in melanoma and their limitations. We propose several approaches to refine our screening models to enhance the discovery process. It is hoped that this discussion will stimulate further improvements in our development of small molecules inhibitors for treatment of melanoma patients.
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