Tracheobronchial calcifications in children

Lauren P Golding1, Michael J Walsh, Thomas E Sumner

  • 1Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157-1009, USA. lgolding@wakehealth.edu

Pediatric Radiology
|April 26, 2013
PubMed

Insights

Tracheobronchial calcifications, a rare finding, may be common in children with prosthetic heart valves treated with warfarin sodium. This study suggests a higher prevalence than previously thought.

Area of Science:

  • Pediatric Radiology
  • Cardiology
  • Pharmacology

Background:

  • Tracheobronchial calcifications are infrequently reported in pediatric populations.
  • Clinical observations suggest a potential link between these calcifications and warfarin sodium treatment in children with prosthetic heart valves.

Purpose of the Study:

  • To investigate the hypothesis that tracheobronchial calcifications are more prevalent in children with prosthetic heart valves treated with warfarin sodium than previously documented.
  • To estimate the prevalence of tracheobronchial calcifications in this specific pediatric cohort.

Main Methods:

  • Retrospective review of medical records and imaging studies.
  • Inclusion criteria focused on children who underwent cardiac valve replacement at the institution.

Main Results:

  • Tracheobronchial calcifications were identified in 35% (6 out of 17) of the studied children on chest radiographs.
  • The prevalence suggests this finding may be frequently overlooked in routine imaging.

Conclusions:

  • All children with identified tracheobronchial calcifications had received warfarin sodium anticoagulation post-surgery.
  • The findings indicate that tracheobronchial calcifications are not uncommon in pediatric patients treated with warfarin.
  • Further research is warranted to establish a potential cause-effect relationship.
Abstract

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