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Published on: August 28, 2018
Tracheobronchial calcifications in children
Lauren P Golding1, Michael J Walsh, Thomas E Sumner
1Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157-1009, USA. lgolding@wakehealth.edu
Insights
Tracheobronchial calcifications, a rare finding, may be common in children with prosthetic heart valves treated with warfarin sodium. This study suggests a higher prevalence than previously thought.
Area of Science:
- Pediatric Radiology
- Cardiology
- Pharmacology
Background:
- Tracheobronchial calcifications are infrequently reported in pediatric populations.
- Clinical observations suggest a potential link between these calcifications and warfarin sodium treatment in children with prosthetic heart valves.
Purpose of the Study:
- To investigate the hypothesis that tracheobronchial calcifications are more prevalent in children with prosthetic heart valves treated with warfarin sodium than previously documented.
- To estimate the prevalence of tracheobronchial calcifications in this specific pediatric cohort.
Main Methods:
- Retrospective review of medical records and imaging studies.
- Inclusion criteria focused on children who underwent cardiac valve replacement at the institution.
Main Results:
- Tracheobronchial calcifications were identified in 35% (6 out of 17) of the studied children on chest radiographs.
- The prevalence suggests this finding may be frequently overlooked in routine imaging.
Conclusions:
- All children with identified tracheobronchial calcifications had received warfarin sodium anticoagulation post-surgery.
- The findings indicate that tracheobronchial calcifications are not uncommon in pediatric patients treated with warfarin.
- Further research is warranted to establish a potential cause-effect relationship.
Background:
Tracheobronchial calcifications are considered a rare radiologic finding in children. Our clinical experience indicates that this finding is not infrequently seen among children with prosthetic heart valves who have been treated with warfarin sodium.
Objective:
We hypothesized that calcifications of the tracheobronchial tree are more common than previously reported in this patient population.
Materials And Methods:
We reviewed the medical records and imaging studies of children who underwent cardiac valve replacement at our institution to estimate the prevalence.
Results:
Tracheobronchial calcifications were identified on chest radiographs in 6 out of 17 children (35%), indicating that this imaging finding might be frequently overlooked.
Conclusion:
All children positive for tracheobronchial calcifications had been anticoagulated with warfarin sodium between the time of surgery and development of positive imaging findings. Our findings suggest that tracheobronchial calcifications are not uncommon in children treated with warfarin. Further investigation is necessary to determine wether there is a cause-effect relationship in these children.
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