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Updated: May 12, 2026
Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers
Published on: September 4, 2017
Micro/Nanometer-scale fiber with highly ordered structures by mimicking the spinning process of silkworm
Su-Kyoung Chae1, Edward Kang, Ali Khademhosseini
1Department of Biomedical Engineering, College of Health Science, Korea University, Jeongeung-dong, Seongbuk-gu, Seoul, 136-703, Republic of Korea.
Abstract:
A new method for the microfluidic spinning of ultrathin fibers with highly ordered structures is proposed by mimicking the spinning mechanism of silkworms. The self-aggregation is driven by dipole-dipole attractions between polar polymers upon contact with a low-polarity solvent to form fibers with nanostrands. The induction of Kelvin-Helmholtz instabilities at the dehydrating interface between two miscible fluids generates multi-scale fibers in a single microchannel.
