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Published on: March 22, 2012
Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis
G Marshall Lyon1, Deborah Abdul-Ali, Juergen Loeffler
1Emory University School of Medicine, Atlanta, Georgia, USA. gmlyon@emory.edu
Journal of Clinical Microbiology
|April 26, 2013
Abstract:
Twelve laboratories evaluated candidate material for an Aspergillus DNA calibrator. The DNA material was quantified using limiting-dilution analysis; the mean concentration was determined to be 1.73 × 10(10) units/ml. The calibrator can be used to standardize aspergillosis diagnostic assays which detect and/or quantify nucleic acid.
