Related Experiment Video
Updated: May 12, 2026

Sectioning Mammary Gland Whole Mounts for Lesion Identification
Published on: July 24, 2017
Hyperechoic lesions of the breast: radiologic-histopathologic correlation
Beatriz Adrada1, Yun Wu, Wei Yang
1Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
Objective:
Breast ultrasound is helpful in the characterization of masses to differentiate benign from malignant disease. The internal echotexture of a mass is an important ultra-sound feature in breast diagnostic workup. This article reviews the imaging and histopathology findings of benign and malignant hyperechoic masses to better recognize these conditions.
Conclusion:
Hyperechoic masses are frequently benign, including hematoma, fat necrosis, abscess, and benign neoplasm. Malignant hyperechoic lesions include invasive ductal and invasive lobular carcinoma, lymphoma, and sarcoma. Understanding lesion echotexture in the context of clinical and mammographic findings will help establish appropriate diagnoses for hyperechoic masses.

