Related Experiment Video
Updated: May 11, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
Published on: November 15, 2013
[Not Available]
Matthias Bossard1, Michael Kühne, David Conen
1Klinik für Kardiologie, Universitätsspital Basel.
Insights
An irregular pulse requires careful evaluation to distinguish benign findings from serious heart rhythm disorders. Prompt diagnosis and risk stratification are crucial for effective management and improved patient outcomes.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Irregular pulse is a frequent clinical observation.
- Distinguishing benign from potentially harmful arrhythmias is critical.
Purpose of the Study:
- To outline the diagnostic approach for irregular pulse.
- To discuss common causes and management strategies for arrhythmias.
Main Methods:
- Clinical examination and electrocardiography form the primary diagnostic steps.
- Further investigations include laboratory tests, prolonged rhythm monitoring, and cardiac imaging.
Main Results:
- Common causes include respiratory arrhythmia, premature beats, supraventricular and ventricular arrhythmias.
- Atrial fibrillation requires specific treatment and risk stratification.
- Asymptomatic bradyarrhythmias generally do not need intervention unless symptomatic.
Conclusions:
- A systematic diagnostic approach is essential for managing irregular pulses.
- Timely identification and treatment of arrhythmias like atrial fibrillation can improve prognosis.
- Intervention for bradyarrhythmias is guided by symptom correlation.
Abstract:
An irregular pulse is a common finding in daily clinical practice. The underlying rhythm disorders are influenced by the patient's age, cardiac history and other comorbidities. It is of paramount importance to discriminate benign discoveries from potentially harmful heart rhythm disorders. The primary diagnostic approach is a thorough clinical examination followed by electrocardiographic documentation. Depending on the findings, further work-up may be needed: laboratory tests, prolonged rhythm monitoring and cardiac imaging. The causes of an asymptomatic arrhythmic pulse are manifold. Common possible causes are respiratory arrhythmia, premature beats as well as various supraventricular and ventricular arrhythmias. Atrial fibrillation is especially noteworthy, as it is not only associated with an increased morbidity and mortality but also needs specific treatment. Affected persons should undergo thorough risk stratification. Premature atrial contractions and ventricular premature beats are common findings. A high burden may be associated with a subclinical cardiac disease and with increased morbidity and mortality. However, there are patients with idiopathic premature beats without associated cardiac disease. Asymptomatic bradyarrhythmias do mostly not need a therapeutic intervention. Pacemaker placement is only needed if specific symptoms can be linked to the bradyarrhythmia.

