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Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

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Related Experiment Video

Updated: Jul 6, 2026

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
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Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise

Published on: February 20, 2017

Tracheobronchial perfusion during exercise in ponies.

M Manohar1

  • 1Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois at Urbana, Champaign 61801.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|May 1, 1990
PubMed
Summary

During exercise, bronchial blood flow significantly increased by the 10th minute, potentially aiding in body heat dissipation. Tracheal blood flow remained unchanged throughout the exercise period.

Area of Science:

  • Physiology
  • Exercise Physiology
  • Cardiovascular Research

Background:

  • Tracheobronchial circulation during exercise remains largely unexamined.
  • Understanding blood flow dynamics in the airways is crucial for respiratory and cardiovascular health during physical exertion.

Purpose of the Study:

  • To investigate the blood flow to the trachea and bronchi during rest and exercise in healthy ponies.
  • To determine if exercise influences tracheobronchial perfusion and its potential role in thermoregulation.

Main Methods:

  • Utilized radionuclide-labeled microspheres injected into the left ventricle to measure blood flow in resting and exercising ponies.
  • Monitored heart rate and mean aortic pressure, with blood flow determined from aortic reference samples.
  • Exercise was performed on a treadmill at 25 km/h, with measurements taken at the 3rd and 10th minutes.

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Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
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Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise

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Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion
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Main Results:

  • Resting tracheal blood flow was significantly lower than bronchial blood flow.
  • Tracheal perfusion showed no significant changes during exercise.
  • Bronchial blood flow remained stable at the 3rd minute of exercise but increased dramatically by the 10th minute.
  • Renal blood flow decreased during the 10th minute of exertion.

Conclusions:

  • Bronchial circulation significantly increases during prolonged exercise, suggesting a role in dissipating metabolic heat.
  • Tracheal circulation appears less affected by exercise compared to bronchial circulation.
  • These findings highlight the dynamic nature of airway perfusion in response to physiological stress.