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The RETRIEVE trial: safety and effectiveness of the retrievable crux vena cava filter

H Bob Smouse1, Robert Mendes, Marc Bosiers

  • 1Department of Vascular and Interventional Radiology, OSF St. Francis Medical Center, 530 NE Glen Oak, Peoria IL 61637, USA. bsmouse@cirarad.com

Journal of Vascular and Interventional Radiology : JVIR
|April 30, 2013
PubMed

Insights

The Crux vena cava filter demonstrated safety and effectiveness in preventing pulmonary embolism (PE). This clinical trial showed high success rates for deployment, retrieval, and overall patient outcomes.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Pulmonary embolism (PE) poses a significant risk to patient health.
  • Inferior vena cava (IVC) filters are used to prevent PE in high-risk patients.
  • Evaluating new IVC filter devices is crucial for improving patient safety and treatment efficacy.

Purpose of the Study:

  • To assess the safety and effectiveness of the Crux vena cava filter.
  • To determine the clinical success rate of the Crux filter in patients at risk for PE.
  • To evaluate device-related adverse events and retrieval success.

Main Methods:

  • Prospective, international, multicenter, single-arm clinical trial.
  • 125 patients implanted with the Crux filter.
  • 180-day follow-up post-placement and 30-day post-retrieval.

Main Results:

  • Clinical success rate of 96.0% (120/125 patients).
  • High technical success (98.4%) and retrieval success (98.1%).
  • Low rates of definite PE (2.4%) and no device migration or fracture observed.

Conclusions:

  • The Crux vena cava filter is safe and effective for PE prevention.
  • Achieved high clinical, technical, and retrieval success rates.
  • Demonstrated a favorable safety profile in a large patient cohort.
Abstract

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