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Updated: May 11, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Nonaccidental head injury
T Roujeau1, E Mireau, M Bourgeois
1Department of Pediatric and Functional Neurosurgery, Montpellier, France; Neurosurgery Department, Hôpital Necker-Enfants Malades, Paris, France.
Insights
Nonaccidental head injury in children (NAHI), often abusive head trauma (AHT), presents serious risks. Early diagnosis and intervention are crucial for better outcomes and child protection.
Area of Science:
- Pediatric Neurology
- Child Abuse Pediatrics
- Neurocritical Care
Background:
- Nonaccidental head injury in children (NAHI), primarily abusive head trauma (AHT), is a significant cause of pediatric mortality and morbidity.
- Intracranial lesions, predominantly subdural hematomas, are common, leading to brain edema, intracranial hypertension, and seizures.
- Differential diagnoses include inborn errors of metabolism like glutaric aciduria type 1 and Menkes disease, necessitating specific diagnostic approaches.
Purpose of the Study:
- To highlight the importance of early diagnosis and management of NAHI/AHT.
- To emphasize the critical role of identifying nonaccidental injury for timely intervention and child protection.
- To outline key factors influencing prognosis and the need for specialized monitoring.
Main Methods:
- Clinical assessment and neuroimaging (CT scan) for diagnosis of intracranial lesions.
- Monitoring for seizures, brain edema, and intracranial hypertension.
- Differential diagnosis including metabolic screening for inborn errors of metabolism.
Main Results:
- NAHI/AHT presents with varied symptoms related to intracranial pressure and seizures.
- Specific risk factors (clinical status, age, CT findings, retinal hemorrhage, seizures) are associated with a worse prognosis compared to accidental trauma.
- Close monitoring in neurointensive care units is essential for these children.
Conclusions:
- Prompt recognition of NAHI/AHT is vital for initiating appropriate emergency treatment and protective measures.
- Effective management involves controlling seizures, preventing recurrence, and reducing intracranial pressure.
- Identifying the nonaccidental nature of the injury is paramount for child protection, involving social evaluation and legal reporting.
Abstract:
Nonaccidental head injury in children (NAHI), most often due to abusive head trauma (AHT), is not uncommon and carries a high risk of mortality and morbidity. Intracranial lesions encountered are mainly subdural hematomas. Despite heterogeneous clinical presentation, symptoms are related to brain edema with intracranial hypertension and/or seizures that should prompt early diagnosis and treatment. Two main differential diagnoses are glutaric aciduria type 1 and Menkes disease, two inborn errors of metabolism that require specific diagnostic procedures and treatment. The aim of emergency treatment is to control seizures, prevent seizure recurrence, and decrease intracranial pressure. Because NAHI/AHT carries a worse prognosis than accidental head traumatism - with specific risk factors such as initial clinical status, age, aspect of initial CT scan, associated retinal hemorrhage, seizure recurrence - these children need close clinical, neurological, and radiological monitoring in neurointensive care units. It is therefore important to identify the nonaccidental origin of the injury at the earliest opportunity so that the appropriate intervention, including social evaluation and reporting suspected cases to judicial authorities, can be made to protect the child from further harm.
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