Related Experiment Video
Updated: May 11, 2026
Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
Cardiac magnetic resonance analysis of right ventricular function: comparison of quantification in the short-axis and
M Souto Bayarri1, L Masip Capdevila1, C Remuiñan Pereira1
1Departamento de Radiología, Complejo Hospitalario Universitario de Santiago (CHUS), Universidad de Santiago de Compostela (USC), Santiago de Compostela, España.
Objective:
To compare the methods of right ventricle segmentation in the short-axis and 4-chamber planes in cardiac magnetic resonance imaging and to correlate the findings with those of the tricuspid annular plane systolic excursion (TAPSE) method in echocardiography.
Material And Methods:
We used a 1.5T MRI scanner to study 26 patients with diverse cardiovascular diseases. In all MRI studies, we obtained cine-mode images from the base to the apex in both the short-axis and 4-chamber planes using steady-state free precession sequences and 6mm thick slices. In all patients, we quantified the end-diastolic volume, end-systolic volume, and the ejection fraction of the right ventricle. On the same day as the cardiac magnetic resonance imaging study, 14 patients also underwent echocardiography with TAPSE calculation of right ventricular function.
Results:
No statistically significant differences were found in the volumes and function of the right ventricle calculated using the 2 segmentation methods. The correlation between the volume estimations by the two segmentation methods was excellent (r=0,95); the correlation for the ejection fraction was slightly lower (r=0,8). The correlation between the cardiac magnetic resonance imaging estimate of right ventricular ejection fraction and TAPSE was very low (r=0,2, P<.01).
Conclusion:
Both ventricular segmentation methods quantify right ventricular function adequately. The correlation with the echocardiographic method is low.
