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Updated: May 11, 2026
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Single Port Donor Nephrectomy
Published on: March 12, 2011
Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a 5-year,
Jodi A Antonelli1, Aditya Bagrodia, Christopher Odom
1Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
European Urology
|April 30, 2013
Summary
Laparoendoscopic single-site nephrectomy (LESS-N) offers shorter hospital stays and reduced blood loss compared to traditional laparoscopic nephrectomy (LN). This minimally invasive approach is safe and effective for selected patients, though further trials are needed.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Surgical Oncology
Background:
- Laparoscopic nephrectomy (LN) is the standard for kidney removal.
- Laparoendoscopic single-site nephrectomy (LESS-N) represents an advancement in minimally invasive techniques.
Purpose of the Study:
- To compare the 5-year outcomes of LESS-N with conventional LN.
- To evaluate the safety and efficacy of LESS-N.
Main Methods:
- A retrospective, case-control study matched 47 LESS-N cases with 94 LN controls.
- Data were collected between 2007-2012 for LESS-N and 1999-2009 for LN.
- Statistical analysis included chi-squared and Mann-Whitney tests.
Main Results:
- LESS-N patients had significantly lower body mass index and shorter hospital stays (49 vs. 70 hours).
- Estimated blood loss was significantly lower in the LESS-N group (56 vs. 137 ml).
- No significant differences were observed in operative time, hematocrit/creatinine changes, analgesic use, or complication rates.
Conclusions:
- LESS-N is a safe and durable option for carefully selected nephrectomy patients.
- Further multi-institutional randomized trials are necessary to validate these findings.
