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Updated: May 11, 2026

10:35
Extracellular Glucose Depletion as an Indirect Measure of Glucose Uptake in Cells and Tissues Ex Vivo
Published on: April 6, 2022
Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in
Ala Jo1, Jongmin Park, Seung Bum Park
1Department of Chemistry, Seoul National University, Seoul, Korea.
Abstract:
Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.

