Related Experiment Video
Updated: May 11, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Preparation and properties of α-calcium sulphate hemihydrate and β-tricalcium phosphate bone substitute
Keya Mao1, Feihu Zhou, Fuzai Cui
1Department of Orthopedics, General Hospital of People's Liberation Army, Beijing, China.
Abstract:
Autogenous bone graft carries the risk of complications. In contrast, artificial bone graft provides initial strength and allows new bone ingrowth. In this study, we examined methods of preparation of α-calcium sulphate hemihydrate (α-CSH) and β-tricalcium phosphate (β-TCP), and a composite of the two materials. Characterization of the materials was determined with X-ray diffraction, differential thermal analysis (DTA), scanning electron microscopy (SEM), and porosity analysis. β-TCP exhibited the spatial structure and porosity of normal bone with a macropore size of 50-400 μm and some 1 μm micropores. α-CSH exhibited a regular crystal structure. A combined material was prepared in a 1:1 weight ratio, and in a rabbit model, the rate of new bone mineralization was similar to that of autogenous bone graft. The combined material of β-TCP and α-CSH in this study may provide similar efficacy as autogenous bone graft.
More Related Videos
05:41Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
09:35Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
Related Concept Videos
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Sulfate Attack on Concrete
Sulfates from sources like soil, groundwater, or industrial effluents...
Hydration of Cement
The Bone Matrix
Bone Remodeling
Skeleton and Calcium Homeostasis