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Updated: May 11, 2026

Hydrolysis of a Ni-Schiff-Base Complex Using Conditions Suitable for Retention of Acid-labile Protecting Groups
Published on: April 6, 2017
Spectroscopic studies of amino acid ionic liquid-supported Schiff bases
Paula Ossowicz1, Ewa Janus, Grzegorz Schroeder
1Department of Inorganic and Analytical Chemistry, West Pomeranian University of Technology, Szczecin, Al. Piastów 42, Szczecin 71-065, Poland.
Abstract:
Amino acid ionic liquid-supported Schiff bases, derivatives of salicylaldehyde and various amino acids (L-threonine, L-valine, L-leucine, L-isoleucine and L-histidine) have been investigated by means of various spectroscopic techniques (NMR, UV-Vis, IR, MS) and deuterium isotope effects on ¹³C-NMR chemical shifts. The results have shown that in all studied amino acid ionic liquid-supported Schiff bases (except the L-histidine derivative) a proton transfer equilibrium exists and the presence of the COO⁻ group stabilizes the proton transferred NH-form.
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