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Updated: May 11, 2026
07:51
Synovial Fluid Analysis to Identify Osteoarthritis
Published on: October 20, 2022
Synovial sarcoma of the foot
Mikhail Bekarev1, Elisabeth C Elsinger, Esperanza Villanueva-Siles
1Albert Einstein College of Medicine, Bronx, New York, USA.
Summary
A man initially treated for lung cancer developed a foot mass misdiagnosed as Morton's neuroma. Further evaluation revealed the foot mass was synovial sarcoma, with the lung lesion being metastatic disease.
Area of Science:
- Oncology
- Orthopedic Oncology
- Surgical Pathology
Background:
- A 75-year-old male underwent lung lobectomy for a presumed primary lung malignancy.
- Post-operatively, the patient developed a painful foot mass, initially suspected to be Morton's neuroma.
Observation:
- The foot mass was located between the third and fourth metatarsal heads.
- Extensive oncologic workup was initiated to determine the nature of the foot mass.
Findings:
- The foot mass was definitively diagnosed as a synovial sarcoma.
- Retrospective analysis confirmed the initial lung lesion was a metastasis from the synovial sarcoma.
Implications:
- This case highlights the importance of comprehensive oncologic evaluation for unusual presentations.
- Synovial sarcoma can metastasize to unusual sites, mimicking benign conditions.
- Accurate diagnosis is crucial for appropriate treatment and patient management.
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