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Transition metal-catalyzed functionalization of pyrazines

Nicolai I Nikishkin1, Jurriaan Huskens, Willem Verboom

  • 1Laboratory of Molecular Nanofabrication, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.

Organic & Biomolecular Chemistry
|May 2, 2013
PubMed
Summary

Transition metal catalysis enables key carbon-carbon and carbon-heteroatom bond formations in pyrazines. This review covers recent advances in palladium-catalyzed cross-coupling reactions for pyrazine functionalization.

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