Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is to...
Parkinson Disease l: Introduction01:24

Parkinson Disease l: Introduction

Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of which...
Parkinson Disease ll: Pathophysiology01:24

Parkinson Disease ll: Pathophysiology

Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Anatomical Movements00:51

Anatomical Movements

Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist, metacarpophalangeal,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cognitive test performance in CLN3 Disease is associated with the CLN3 Staging System (CLN3SS).

medRxiv : the preprint server for health sciences·2026
Same author

Incidence of pediatric chronic tic disorders and feasibility of using the Massachusetts All-Payer Claims Database, 2012-2016.

Equity neuroscience·2026
Same author

Diagnostic approach to episodic ataxia types 1 and 2: a proposed algorithm for limited resource-settings.

Frontiers in neurology·2026
Same author

Recommendations for the diagnosis and management of cln3 disease (batten disease) using the Delphi consensus methodology.

Orphanet journal of rare diseases·2026
Same author

A proposed preintervention framework for neurosurgery in children with medically refractory hypertonia: a scoping review.

Journal of neurosurgery. Pediatrics·2026
Same author

A timeline of symptom onset and disease progression in CLN3 disease.

Orphanet journal of rare diseases·2026
Same journal

Efficacy and Safety of Perampanel in Patients With Brain Tumor-Related Epilepsy: A Systematic Review and Meta-Analysis.

Neurology. Clinical practice·2026
Same journal

Patient-Reported Symptom Burden in Individuals With Parkinson Disease.

Neurology. Clinical practice·2026
Same journal

Global Access to Diagnostic Paraclinical Testing Incorporated in the 2024 Revised McDonald Criteria: Disparities and Opportunity.

Neurology. Clinical practice·2026
Same journal

Clinical Differentiation of Self-Limited Epilepsy With Autonomic Seizures (Panayiotopoulos Syndrome) and Childhood Migraine.

Neurology. Clinical practice·2026
Same journal

The National Association of Epilepsy Centers Accreditation Criteria Should Include Care for People With Functional/Dissociative Seizures.

Neurology. Clinical practice·2026
Same journal

Long-Term Outcomes in Antibody-Negative Autoimmune Encephalitis: A Systematic Review and Meta-Analysis.

Neurology. Clinical practice·2026
See all related articles

Related Experiment Video

Updated: May 11, 2026

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable
09:24

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable

Published on: May 17, 2024

Pediatric movement disorders: Five new things.

Joanna S Blackburn1, Jonathan W Mink, Erika F Augustine

  • 1Division of Neurology (JSB), Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; and Division of Child Neurology (JWM, EFA), Department of Neurology, University of Rochester Medical Center, Rochester, NY.

Neurology. Clinical Practice
|May 2, 2013
PubMed
Summary
This summary is machine-generated.

Pediatric movement disorders require better definitions and research for improved treatment. Progress in genetics, clinical understanding, and trials aims to enhance care for affected children.

More Related Videos

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
07:20

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy

Published on: August 9, 2024

Related Experiment Videos

Last Updated: May 11, 2026

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable
09:24

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable

Published on: May 17, 2024

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
07:20

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy

Published on: August 9, 2024

Area of Science:

  • Neurology
  • Pediatrics
  • Genetics

Background:

  • Pediatric movement disorders lack consensus definitions and evidence-based treatments.
  • Current treatment approaches rely on clinical experience due to limited clinical trials.

Purpose of the Study:

  • To review advancements in pediatric movement disorders.
  • To highlight 5 key areas of progress for improved diagnosis and care.

Main Methods:

  • Literature review focusing on recent research in pediatric movement disorders.
  • Analysis of progress in defining disorders, identifying genes, understanding clinical presentations, and conducting clinical trials.

Main Results:

  • Progress is being made in establishing consensus definitions.
  • Identification of causative genes is advancing understanding of disease etiology.
  • Clinical trials are beginning to emerge, offering hope for evidence-based treatments.

Conclusions:

  • Consensus definitions, genetic insights, and clinical trials are crucial for advancing pediatric movement disorder care.
  • Continued research in these 5 highlighted areas will lead to better diagnostic and therapeutic strategies for children.