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Fluoxetine and the bleeding time
J E Humphries1, M S Wheby, S R VandenBerg
1Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville 22908.
Archives of Pathology & Laboratory Medicine
|July 1, 1990
Abstract:
Fluoxetine (Prozac) is a nontricyclic serotonin (5-hydroxytryptamine) reuptake inhibitor commonly prescribed for the treatment of depression. Fluoxetine also blocks 5-hydroxytryptamine reuptake in platelets and could potentially lead to clinically significant platelet dysfunction. We describe a patient who developed petechiae and prolongation of the bleeding time while receiving fluoxetine therapy.
