Related Experiment Video
Updated: May 11, 2026

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration
Published on: June 15, 2018
Multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, and other chronic
Mazen M Dimachkie1, Richard J Barohn, Jonathan Katz
1Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Boulevard, Mail Stop 2012, Kansas City, KS 66160, USA. mdimachkie@kumc.edu
Abstract:
Chronic acquired demyelinating neuropathies (CADP) constitute an important group of immune neuromuscular disorders affecting myelin. This article discusses CADP with emphasis on multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, distal acquired demyelinating symmetric neuropathy, and less common variants. Although each of these entities has distinctive laboratory and electrodiagnostic features that aid in their diagnosis, clinical characteristics are of paramount importance in diagnosing specific conditions and determining the most appropriate therapies. Knowledge regarding pathogenesis, diagnosis, and management of these disorders continues to expand, resulting in improved opportunities for identification and treatment.
Related Concept Videos
Multiple Sclerosis l: Introduction
Diabetic Neuropathy
Myasthenia Gravis ll: Pathophysiology
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Cardiomyopathy I: Introduction and Classification
Alterations in Muscle Tone ll

