Live mammalian cell arrays
Related Experiment Video
Updated: May 11, 2026
Live-cell Imaging of Single-Cell Arrays (LISCA) - a Versatile Technique to Quantify Cellular Kinetics
Published on: March 18, 2021
Kristina Woodruff1, Luis M Fidalgo, Samy Gobaa
1Institute of Bioengineering, School of Engineering and School of Life Science, École Polytechnique Fédérale de Lausanne, Switzerland.
Abstract:
High-content assays have the potential to drastically increase throughput in cell biology and drug discovery, but handling and culturing large libraries of cells such as primary tumor or cancer cell lines requires expensive, dedicated robotic equipment. We developed a simple yet powerful method that uses contact spotting to generate high-density nanowell arrays of live mammalian cells for the culture and interrogation of cell libraries.
