Extracorporeal Life Support Organization Registry Report 2012

Area of Science:

• Cardiovascular and Respiratory Medicine
• Pediatric Critical Care
• Neonatal Intensive Care

Background:

• Extracorporeal Life Support Organization (ELSO) Registry Reports provide comprehensive data on extracorporeal life support (ECLS) utilization.
• Nearly 51,000 patients have received ECLS, highlighting its widespread application in critical care.

Purpose of the Study:

• To present summary data from the ELSO Registry Reports through July 2012.
• To analyze trends and survival rates for ECLS across different patient populations (neonatal, pediatric, adult) and indications (respiratory, cardiac failure).

Main Methods:

• Analysis of summary data from the international ELSO Registry Reports up to July 2012.
• Categorization of patients by age group (neonatal, pediatric, adult) and primary diagnosis (respiratory failure, cardiac support).

Main Results:

• Neonatal respiratory failure (50% of patients) demonstrated a 75% survival rate, with congenital diaphragmatic hernia being a common indication.
• Pediatric respiratory failure ECLS use doubled since 2000 (56% survival), while adult respiratory failure ECLS cases increased significantly post-2009 (55% survival).
• ECLS for cardiac support showed consistent growth, with survival rates of 40% (neonates), 49% (pediatrics), and 39% (adults).

Conclusions:

• ECLS is a critical intervention for severe respiratory and cardiac failure across all age groups.
• Significant increases in ECLS use for adult respiratory failure were observed, particularly following the H1N1 pandemic and CESAR trial.
• ECLS offers a vital support option with varying but notable survival rates for complex pediatric and neonatal conditions.