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Related Concept Videos

Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
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Cell Motility through Blebbing01:16

Cell Motility through Blebbing

Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
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Related Experiment Video

Updated: May 11, 2026

Cell Patterning Using Magnetic-Archimedes Strategy
05:09

Cell Patterning Using Magnetic-Archimedes Strategy

Published on: February 2, 2024

Magnetically-controllable zigzag structures as cell microgripper.

Tzong-Rong Ger1, Hao-Ting Huang, We-Yun Chen

  • 1Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu 300, Taiwan.

Lab on a Chip
|May 7, 2013
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel micro-scaled cell gripper using magnetic zigzag structures. This device can precisely grip single cells in solution, paving the way for advanced biochip applications.

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Magnetic Tweezers for the Measurement of Twist and Torque
11:41

Magnetic Tweezers for the Measurement of Twist and Torque

Published on: May 19, 2014

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Last Updated: May 11, 2026

Cell Patterning Using Magnetic-Archimedes Strategy
05:09

Cell Patterning Using Magnetic-Archimedes Strategy

Published on: February 2, 2024

Magnetic Tweezers for the Measurement of Twist and Torque
11:41

Magnetic Tweezers for the Measurement of Twist and Torque

Published on: May 19, 2014

Area of Science:

  • Microfluidics
  • Biotechnology
  • Materials Science

Background:

  • Cell manipulation is crucial for various biological and medical applications.
  • Existing microgripping technologies face challenges in precision and biocompatibility.
  • Magnetic actuation offers a promising non-contact method for micro-scale manipulation.

Purpose of the Study:

  • To design and fabricate a novel micro-scaled cell gripper.
  • To investigate the magnetic actuation of flexible zigzag structures for precise cell handling.
  • To demonstrate the gripper's capability for single-cell manipulation in aqueous environments.

Main Methods:

  • Fabrication of micro-scaled grippers using flexible magnetic zigzag structures.
  • Deposition of elongated single domain magnetic thin films with high magnetic shape anisotropy.
  • Actuation of the gripper using an external magnetic field to control torque.
  • Measurement of zigzag structure displacement and observation of actuation hysteresis.
  • Demonstration of single-cell gripping in a water solution.

Main Results:

  • Successful fabrication of a micro-scaled cell gripper.
  • Demonstrated controlled actuation of zigzag structures via magnetic fields.
  • Observed hysteresis in the actuation response.
  • Successfully demonstrated gripping of a single cell in water.

Conclusions:

  • The developed magnetic micro-gripper offers precise, non-contact cell manipulation capabilities.
  • The device shows potential for integration into future biochip and biomedical systems.
  • Magnetic actuation provides a robust mechanism for controlling micro-scale devices for biological applications.