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Graves' thyrotoxicosis-induced reversible cardiomyopathy: a case report

Ahmad S Al-Ghamdi1, Naji Aljohani

  • 1Specialized Diabetes and Endocrine Center, King Fahad Medical City, Riyadh, Saudi Arabia.

Clinical Medicine Insights. Case Reports
|May 7, 2013
PubMed

Insights

Graves

Area of Science:

  • Cardiology
  • Endocrinology

Background:

  • Graves' disease is an autoimmune disorder causing hyperthyroidism.
  • Thyrotoxicosis, a state of excess thyroid hormone, can have significant cardiovascular effects.

Observation:

  • A 26-year-old woman presented with severe congestive heart failure.
  • Echocardiography revealed dilated cardiomyopathy with a left ventricular ejection fraction of 20%.

Findings:

  • The patient was diagnosed with cardiomyopathy secondary to Graves' thyrotoxicosis.
  • Treatment with anti-thyroid agents resulted in rapid clinical improvement and ejection fraction normalization.

Implications:

  • Graves' thyrotoxicosis can induce reversible cardiomyopathy, even in young individuals.
  • Cardiomyopathy should be considered in the differential diagnosis of heart failure in patients with Graves' disease.

Keywords:
Graves’ diseasecardiomyopathycongestive heart failurethyrotoxicosis

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