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Updated: May 11, 2026

Extraction of Plant-based Capsules for Microencapsulation Applications
Published on: November 9, 2016
Lycospidine A, a new type of Lycopodium alkaloid from Lycopodium complanatum
Jin-Tang Cheng1, Fei Liu, Xiao-Nian Li
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany , Chinese Academy of Sciences, Kunming 650201, People's Republic of China, and University of Chinese Academy of Sciences , Beijing 100049, People's Republic of China.
Abstract:
Lycospidine A (1), the first example of a Lycopodium alkaloid which contains an unprecedented five-membered A ring, was isolated from Lycopodium complanatum. The unique five-membered A ring in 1 indicates that carbons 2-5 in 1 are presumably derived from proline instead of the lysine biosynthetically, which suggests that 1 represent a new class of Lycopodium alkaloid. In addition, the unique structural feature and biosynthetic origin of 1 shed new insight into the structural diversity of Lycopodium alkaloid analogue libraries potentially accessible by engineered biosynthesis.
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