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Related Concept Videos

Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Drug Administration and Therapy Phases: Overview01:26

Drug Administration and Therapy Phases: Overview

Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Blind Procedures02:07

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Related Experiment Video

Updated: May 11, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
23:53

Ole Isacson: Development of New Therapies for Parkinson's Disease

Published on: April 29, 2007

Treatment development: can we find a better way?

Steven C Hayes1, Douglas M Long, Michael E Levin

  • 1Department of Psychology, University of Nevada, Reno, NV 89557-0062, USA. hayes@unr.edu

Clinical Psychology Review
|May 8, 2013
PubMed
Summary

Traditional treatment development is inadequate. Future progress requires greater philosophical clarity, theoretical development, and practical considerations for effective and clinically useful innovations in applied psychology.

Keywords:
Contextual behavioral scienceFunctional analysisStage modelTheoryTreatment development

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A Treatment Package without Escape Extinction to Address Food Selectivity
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Last Updated: May 11, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
23:53

Ole Isacson: Development of New Therapies for Parkinson's Disease

Published on: April 29, 2007

A Treatment Package without Escape Extinction to Address Food Selectivity
04:23

A Treatment Package without Escape Extinction to Address Food Selectivity

Published on: August 21, 2015

Area of Science:

  • Psychology
  • Philosophy of Science

Background:

  • Traditional treatment development models (technological, stage, functional analysis) are insufficient.
  • Current approaches lack theoretical depth, practicality, and client-practitioner fit.

Purpose of the Study:

  • To advocate for a more coherent and philosophically grounded approach to treatment development.
  • To emphasize the need for integrating basic and applied psychology in innovation.

Main Methods:

  • Philosophical analysis of existing treatment development paradigms.
  • Argument for enhanced theoretical development and practical considerations.

Main Results:

  • Identified inadequacies in current treatment development strategies.
  • Proposed a framework emphasizing philosophical clarity, theoretical integration, and practical utility.

Conclusions:

  • Treatment innovation requires a paradigm shift towards greater theoretical rigor and practical relevance.
  • Integrating basic and applied psychology is crucial for scientifically progressive and clinically useful advancements.