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Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
Management of patent ductus arteriosus in preterm infants: clinical judgment might be a fair option
Serdar Alan1, Cem Karadeniz, Emel Okulu
1Department of Pediatrics-Neonatology and.
Insights
Clinical signs and echocardiography help decide patent ductus arteriosus (PDA) treatment in preterm infants. Many PDAs close spontaneously, avoiding unnecessary interventions.
Area of Science:
- Neonatal Medicine
- Pediatric Cardiology
- Medical Imaging
Background:
- Patent ductus arteriosus (PDA) is common in preterm infants.
- Treatment decisions for PDA often rely on clinical and echocardiographic data.
- Evaluating the necessity of PDA treatment is crucial to avoid potential complications.
Purpose of the Study:
- To determine the percentage of preterm infants requiring PDA treatment.
- To assess the role of clinical symptoms alongside echocardiography in PDA treatment decisions.
- To investigate the impact of combining clinical and echocardiographic findings for PDA management.
Main Methods:
- Daily echocardiographic evaluations were performed on 39 preterm infants (≤29 weeks' gestation).
- Infants with PDA were monitored for clinical symptoms until spontaneous or treated closure.
- Treatment decisions were guided by a combination of clinical signs and echocardiographic findings.
Main Results:
- PDA was detected in 64% of infants (25 out of 39).
- 41% of infants experienced spontaneous PDA closure or minimal shunting before symptom onset.
- Symptomatic infants (23%) showed significantly higher ductus size/BW and LA/Ao root ratios.
Conclusions:
- Correlating clinical signs with echocardiographic findings is appropriate for PDA treatment decisions.
- This approach can help prevent unnecessary medical interventions for PDA in preterm infants.
- Careful assessment can identify infants who may not require active treatment for PDA.
Objective:
The objective of this study was to find out the percentage of preterm infants that needed treatment for patent ductus arteriosus (PDA), when treatment decision was based on clinical signs and symptoms, besides echocardiographic findings.
Methods:
Daily echocardiographic evaluation was conducted in 39 preterms ≤29(6/7) weeks' gestation. Patients with ductus arteriosus were closely followed-up for clinical symptoms of PDA for treatment decision until ductus arteriosus was closed either spontaneously or by treatment.
Results:
PDA was found in 25 (64%) infants. Mean gestational age and birth weight (BW) of the patients with PDA were 27.8 ± 1.2 and 998 ± 221 g, respectively. PDA closed spontaneously or had minimal ductal shunting before any signs and symptoms attributable to PDA were observed in 16 (41%) infants. Mean ductus size/BW ratio and mean left atrial/aortic root ratio were significantly higher in 9 (23%) symptomatic patients (2.06 ± 0.75 versus 1.32 ± 0.75 mm, p = 0.012 and 1.31 ± 0.52 versus 1.19 ± 0.2 mm, p = 0.043, respectively). PDA closure was observed after the first dose of ibuprofen in six of nine patients.
Conclusion:
Correlation of clinical signs with echocardiographic findings for the decision of PDA treatment can be appropriate to prevent unnecessary medical treatments.
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