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Related Experiment Video

Updated: May 11, 2026

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Published on: January 8, 2014

Engineering fluid flow using sequenced microstructures.

Hamed Amini¹, Elodie Sollier, Mahdokht Masaeli

¹Department of Bioengineering, University of California, 420 Westwood Plaza, 5121 Engineering V, PO Box 951600, Los Angeles, California 90095, USA.

Nature Communications

|May 9, 2013

Summary

This summary is machine-generated.

Researchers engineered ordered fluid streams using pillar sequences, moving beyond chaotic mixing. This method precisely controls fluid shapes and behaviors for applications in automation and biomolecular interactions.

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Last Updated: May 11, 2026

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Patterning of Microorganisms and Microparticles through Sequential Capillarity-assisted Assembly

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Published on: November 4, 2021

Area of Science:

Fluid dynamics
Microfluidics
Engineering

Background:

Controlling fluid stream shapes is crucial for industrial processes and biomolecular interactions.
Existing methods often rely on chaotic flows to enhance mixing, limiting precise control.

Purpose of the Study:

To develop a novel approach for controlling fluid streams by applying order through sequences of transformations.
To engineer complex fluid structures and behaviors without relying on chaotic mixing or numerical simulations.

Main Methods:

Investigated inertial flow deformations around single cylindrical pillars in a microfluidic channel.
Assembled net fluid transformations from pillar interactions to engineer fluid streams.
Sequentially arranged pillars to create deterministic mappings for complex fluid structures.

Main Results:

Demonstrated sculpting of fluid stream cross-sections into complex geometries.
Achieved fluid stream manipulation, including moving, splitting, and solution exchange.
Successfully performed particle separation using the engineered fluid streams.

Conclusions:

Developed a general strategy to engineer fluid streams into defined configurations by abstracting fluid motion complexity.
This approach represents a first step towards programming fluid streams of any desired shape for automation.
Potential applications include biological, chemical, and materials automation.