Related Experiment Video
Updated: May 11, 2026

07:19
Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
Published on: August 4, 2021
Light-inducible molecular beacons for spatio-temporally highly defined activation
Jennifer S Rinne1, Tim P Kaminski, Ulrich Kubitscheck
1Goethe University Frankfurt, Institute for Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Max-von-Laue-Str. 9, 60438 Frankfurt, Germany.
Abstract:
We have developed a new molecular beacon design that requires an additional UV pulse for fluorescence activation. This improves the signal-to-noise ratio tremendously compared to previous approaches and allows for a precise control of the time point and location of RNA labelling.

