Undesirable effects after treatment with dermal fillers

Area of Science:

• Dermatology
• Cosmetic Procedures
• Aesthetic Medicine

Background:

• Soft tissue augmentation is a common cosmetic dermatology procedure.
• Nonanimal hyaluronic acid (HA) is a widely used filler for facial rejuvenation.
• HA fillers address lip augmentation, nasolabial folds, marionette lines, and dynamic wrinkles.

Purpose of the Study:

• To assess the types and management of adverse events associated with nonanimal cross-linked HA.
• To analyze complications observed over a three-year period in a cosmetic unit.

Main Methods:

• A retrospective review of patients experiencing complications after HA filler treatment.
• Classification of adverse reactions into immediate, early-onset, and late-onset categories.
• Documentation of treatment strategies for each complication type.

Main Results:

• Twenty-three patients reported complications post-HA augmentation.
• Immediate complications (10 cases) treated with hyaluronidase, massage, and antibiotics.
• Early- (8 cases) and late-onset (5 cases) complications managed with intralesional triamcinolone acetonide.
• Most patients showed improvement, except for one with recurrent granulomas.

Conclusions:

• Undesirable effects of HA fillers are infrequent.
• Timely and appropriate treatment leads to favorable outcomes for most complications.
• Awareness of potential adverse events is crucial for physicians to prevent complications and sequelae.