Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inhibitors of Viral Protein Synthesis

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...

Subviral Agents

Subviral Agents

Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...

Retrovirus Life Cycles

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Factors Predicting the Extent to which STEM Students Value Cross-Disciplinary Skills: A Study across Four Institutions.

CBE life sciences education·2023

Same author

The Conceptualization of Quantitative Reasoning among Introductory Biology Faculty.

Journal of microbiology & biology education·2021

Same author

An integrated model for interdisciplinary graduate education: Computation and mathematics for biological networks.

PloS one·2021

Same author

Enhancing Graduate Students' Ability to Conduct and Communicate Research through an Interdisciplinary Lens.

Journal of microbiology & biology education·2019

Same author

Development, Validation, and Application of the Microbiology Concept Inventory.

Journal of microbiology & biology education·2018

Same author

Concept Inventory Development Reveals Common Student Misconceptions about Microbiology.

Journal of microbiology & biology education·2018

Search research articles

Related Experiment Video

Updated: May 11, 2026

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

Published on: October 29, 2015

Antiviral drug research proposal activity.

Lisa Injaian¹, Ann C Smith, Jennifer German Shipley

¹University of Maryland, College Park, MD 20742.

Journal of Microbiology & Biology Education

|May 9, 2013

Summary

This learning activity enhanced student understanding of combining basic and clinical research for developing antiviral drugs. Students improved their knowledge of the scientific process and virology research.

More Related Videos

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

Related Experiment Videos

Last Updated: May 11, 2026

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

Published on: October 29, 2015

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

Area of Science:

Virology
Medical Education
Drug Development

Background:

Antiviral drug development requires integrating basic and clinical research.
Effective learning strategies are crucial for understanding complex scientific processes.
Students need enhanced information literacy in specialized scientific fields like virology.

Purpose of the Study:

To design and implement a learning activity fostering an understanding of combined basic and clinical research in antiviral drug development.
To improve students' comprehension of the scientific research process.
To enhance students' information literacy within the field of virology.

Main Methods:

A Research Oriented Learning Activity (ROLA) was developed.
Students worked in teams, specializing in different aspects of antiviral drug design.
The activity culminated in a poster session where students presented Antiviral Drug Research Proposals (ADRPs) to peers and virologists.

Main Results:

The activity significantly increased student awareness and knowledge of the research process.
Students demonstrated a better understanding of the steps involved in developing antiviral drugs.
Enhanced information literacy in virology was observed among participants.

Conclusions:

The Research Oriented Learning Activity effectively demonstrated the synergy between basic and clinical research in drug development.
This pedagogical approach successfully improved students' grasp of scientific inquiry and antiviral drug design.
The project highlighted the importance of collaborative learning and specialized knowledge in scientific research.