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Updated: May 11, 2026

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Development of a Novel Internal Fixation Model for Rat Radial Fractures: Fracture Healing Assessment and Dorsal Root Ganglion Isolation
Published on: March 13, 2026
The development of internal fixation - historical overview.
Aleksandar R Lesić1, Slavisa Zagorac, Vesna Bumbasirević
1University of Belgrade.
Acta Chirurgica Iugoslavica
|May 10, 2013
Summary
Internal fixation revolutionized fracture treatment, evolving from ancient Egyptian methods. Modern advancements like sterilization and antibiotics ensure surgical safety and efficacy.
Area of Science:
- Orthopedic surgery
- Trauma management
Background:
- Fracture treatment has a long history, dating back to ancient Egypt.
- Internal fixation emerged as a significant advancement in fracture care.
Observation:
- The development of internal fixation methods began in the late 18th century.
- Key figures like Lambotte, Lane, Danis, and Groves pioneered its expansion.
- Advancements in sterilization, radiography, anesthesiology, and antibiotics transformed the safety and efficacy of fracture surgery.
Findings:
- Internal fixation, supported by technological and medical progress, became a cornerstone of modern orthopedic practice.
- Pioneering work laid the foundation for the principles of the AO school of fracture treatment.
Implications:
- Continuous innovation introduces new techniques, such as biological internal fixation and minimally invasive procedures.
- Daily integration of novel technologies and devices enhances surgical practice in fracture management.
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