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Published on: December 1, 2023
[Effects of soy protein supplement on overweight and obese population: meta-analysis of randomized controlled trials]
Jing Wu1, Jiayi Dong, Xia Jiang
1Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, China. 403923179@qq.com
Objective:
To study the effects of soy protein supplement on overweight and obese population.
Methods:
Randomized controlled trials (RCT) published from January 1988 to May 2012 observing the effect of soy protein supplement on overweight and obese population were collected. Meta-analysis was applied to estimate the standardized mean difference (WMD) and 95% confidence interval (95% CI).
Results:
Among 13 RCTs, the number of the studies observing change of body weight, body mass index (BMI), fat mass and waist circumference were 12, 7, 7 and 11, respectively. Compared with the control group, the combined WMD (95% CI) of soy protein supplemented was - 1.04 kg [( -1.97) - ( -0.11)], -0.19 kg/m2 [(-0.41) - (0.02)], -0.99 kg [(-1.73) - (-0.24)] and - 0.94 cm [(-1.66) - (-0.21)], respectively. However, the protective effect of soy protein was only observed among studies conducted in Western population, but not in Asian population.
Conclusion:
Soy protein supplementation significantly decreased body weight, fat mass and waist circumference in overweight and obese population.
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