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Updated: May 11, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

[Role of spatio-temporal non uniformities in blood coagulation regulation]

A M Shibeko, F I Ataullakhanov

    Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
    |May 11, 2013
    PubMed

    This paper reviews some contemporary researches of thrombosis and hemostasis process that consider its spatio-temporal dynamics. Among them, there are platelet distribution in the blood vessel and the dependence of the platelet plug growth on the hematocrit level; influence of the tissue factor density on the blood coagulation onset and on the efficacy of some drugs, designed for the hemostasis improvement; regulation of blood coagulation by the flow rate. Mechanisms controlling the mentioned processes are described. Clinical significance and novel diagnostic and therapeutic approaches are discussed from the position of the spatio-temporal non uniformities of thrombosis and hemosatsis.

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