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Published on: July 31, 2017
Two new neuroprotective phenolic compounds from Gastrodia elata
Zhen-Chang Zhang1, Gang Su, Jiong Li
1School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Abstract:
Two new phenolic compounds 4-(4'-hydroxybenzyl) phenyl glucoside (gastrodin B, 1) and 1'-hydroxymethyl-phenyl 4-hydroxy-3-(4″-hydroxybenzyl) benzyl ether (gastrol B, 2) were isolated from the rhizomes of Gastrodia elata. Their structures were elucidated on the basis of spectroscopic data and chemical reaction. All compounds exhibited potent neuroprotective activity against H2O2-induced PC12 cell damage.
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