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Targeting allosteric disulphide bonds in cancer

Philip J Hogg1

  • 1Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Sydney NSW 2052, Australia. p.hogg@unsw.edu.au

Nature Reviews. Cancer
|May 11, 2013
PubMed

Insights

Protein modifications like cleavage and disulphide bonds are altered in cancer. Targeting these allosteric bonds offers potential new cancer therapies.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Oncology

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