Related Experiment Video
Updated: May 11, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Extracorporeal membrane oxygenation cannula malposition in the azygos vein in an infant
Reinis Balmaks1, Kari E Sufficool, Frances V White
1Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA. reinis.balmaks@gmail.com
Introduction:
Misplacement of extracorporeal membrane oxygenation (ECMO) venous cannula in the azygos vein has previously been described only in newborns.
Case:
For the first time, we report an aberrant ECMO cannula placement in the azygos vein in a child outside neonatal period. History of chronic lung disease and ligation of persistent ductus arteriosus leading to elevated right ventricular pressure was the potential risk factor.
Conclusions:
This rare complication should be considered whenever the patient has inadequate venous return on ECMO and it can be easily ruled out with a lateral chest radiograph.
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