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Updated: May 11, 2026

Systematic Bronchoscopy: the Four Landmarks Approach
Published on: June 23, 2023
A study on non-resolving pneumonia with special reference to role of fiberoptic bronchoscopy
Arunabha D Chaudhuri1, Subhasis Mukherjee, Saumen Nandi
1Department of Respiratory Medicine, R.G. Kar Medical College and Hospital, Kolkata, India.
Context:
Non-resolving pneumonia is often an area of concern for pulmonologists. Fiber optic bronchoscopy (FOB) may have a special role in etiologic evaluation of non-resolving pneumonias. There is paucity of recent studies in this field.
Aims:
This study aimed to assess the patients of non-resolving or slowly resolving pneumonia with special emphasis on efficacy of FOB and computed tomography (CT)-guided fine needle aspiration cytology (FNAC) in diagnosis.
Settings And Design:
Prospective, observational study conducted in a tertiary care institute over a period of one year.
Materials And Methods:
After fulfilling the definition of non-resolving pneumonia by clinical and radiological parameters, patients were evaluated by FOB with relevant microbiological, cytological, histopathological investigations and CT scan of thorax. CT-guided FNAC was done in selected cases where FOB was inconclusive.
Results:
Sixty patients were enrolled in the study. Mean age was 51.33 ± 1.71 years with male to female ratio 2:1. Right lung was more commonly involved (65%), and right upper lobe was the commonest site (25%). Pyogenic infection was the commonest etiology (53.3%), bronchogenic carcinoma and tuberculosis accounted for 26.7% and 16.7% cases, respectively. Both, FOB (85.7%) and CT-guided FNAC (91.67%) were very useful for etiological diagnosis of non-resolving pneumonia. Both the procedures were safe, and no major complication was observed.
Conclusions:
Because of the high yield of FOB, it is very useful and safe diagnostic tool for evaluation of non-resolving pneumonia. CT-guided FNAC also gives good yield when cases are properly selected.
Insights
Fiber optic bronchoscopy (FOB) and CT-guided fine needle aspiration cytology (FNAC) are effective diagnostic tools for non-resolving pneumonia. These safe procedures offer high diagnostic yields, aiding pulmonologists in identifying the causes of persistent lung inflammation.
Area of Science:
- Pulmonology
- Diagnostic Imaging
- Interventional Pulmonology
Background:
- Non-resolving pneumonia presents a diagnostic challenge for pulmonologists.
- Fiber optic bronchoscopy (FOB) may play a crucial role in determining the etiology of non-resolving pneumonias.
- There is a limited number of recent studies investigating the utility of FOB in this context.
Purpose of the Study:
- To evaluate patients with non-resolving or slowly resolving pneumonia.
- To assess the diagnostic efficacy of FOB and computed tomography (CT)-guided fine needle aspiration cytology (FNAC).
- To determine the etiological causes of non-resolving pneumonia.
Main Methods:
- Prospective, observational study conducted over one year in a tertiary care setting.
- Patients meeting criteria for non-resolving pneumonia underwent FOB with microbiological, cytological, and histopathological analyses.
- CT-guided FNAC was performed in selected cases where FOB results were inconclusive.
Main Results:
- Sixty patients (mean age 51.33 years, 2:1 male:female ratio) were enrolled.
- Pyogenic infection (53.3%) was the most common cause, followed by bronchogenic carcinoma (26.7%) and tuberculosis (16.7%).
- FOB demonstrated 85.7% utility, and CT-guided FNAC showed 91.67% utility in etiological diagnosis; both procedures were safe.
Conclusions:
- FOB is a highly useful and safe diagnostic tool for evaluating non-resolving pneumonia due to its high diagnostic yield.
- CT-guided FNAC provides good diagnostic yield when applied to appropriately selected patients.
- Both FOB and CT-guided FNAC are valuable adjuncts in the etiological diagnosis of non-resolving pneumonia.
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