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Updated: May 11, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Epidermolysis bullosa pruriginosa triggered by scabies infestation
Jaehwan Kim1, Chee Hoou Loh, Dedee F Murrell
1Department of Dermatology, St George Hospital, Sydney, New South Wales, Australia.
Abstract:
Epidermolysis bullosa pruriginosa (EB-Pr) is an unusual variant of dystrophic EB. Potential genetic disease modifiers and metabolic factors have been investigated, but thus far no specific insight into this phenotype has emerged. We report an in-depth description of three patients diagnosed as having EB-Pr in whom this particular phenotype developed after scabies infestation and dramatically improved after full treatment. This short communication suggests that scabies infestation could be one of the important triggering factors for the development of the EB-Pr phenotype.
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