Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Future Considerations When Considering Partial Thymectomy.

The Annals of thoracic surgery·2026

Same author

Less May Be Enough: Clinical Equipoise for Partial Thymectomy.

The Annals of thoracic surgery·2026

Same author

Natural History, Treatment, Survival, and Causes of Mortality in Patients With Subsolid and Ground-Glass Nodules.

Chest·2026

Same author

Comparison of Oncologic Outcomes After Partial and Total Thymectomy for Stage I Thymomas.

The Annals of thoracic surgery·2025

Same author

The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Application and Interpretation of the Residual Tumor Classification for Lung Cancer-Results from an International Survey Among Pathologists and Thoracic Surgeons.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2024

Same author

Does thymectomy in adults have long-term health consequences?

The Journal of thoracic and cardiovascular surgery·2024

Search research articles

Related Experiment Video

Updated: May 11, 2026

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

Published on: August 9, 2019

The international thymic malignancy interest group.

Frank C Detterbeck¹

¹Yale University School of Medicine, Section of Thoracic Surgery, New Haven, Connecticut 06520-8062, USA. frank.detterbeck@yale.edu

Journal of the National Comprehensive Cancer Network : JNCCN

|May 14, 2013

Summary

Thymic tumors, a rare disease, lack standard treatments. The International Thymic Malignancy Interest Group (ITMIG) now facilitates global collaboration to build evidence for better clinical guidelines.

Area of Science:

Oncology
Rare Diseases
Clinical Research

Background:

Thymic tumors are rare, leading to empiric treatment strategies.
Existing treatment recommendations are based on limited retrospective data.
Global collaboration is needed to advance understanding and treatment.

Purpose of the Study:

To summarize the development and achievements of the International Thymic Malignancy Interest Group (ITMIG).
To highlight ITMIG's role in fostering global collaboration for thymic malignancies.
To outline the foundation ITMIG provides for future evidence-based guidelines.

Main Methods:

Review of ITMIG's organizational development since 2010.
Summary of key accomplishments and infrastructure built by ITMIG.

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Wild-type Blocking PCR Combined with Sanger Sequencing for Detection of Low-frequency Somatic Mutation

Wild-type Blocking PCR Combined with Sanger Sequencing for Detection of Low-frequency Somatic Mutation

Published on: August 23, 2024

Related Experiment Videos

Last Updated: May 11, 2026

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

Published on: August 9, 2019

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Wild-type Blocking PCR Combined with Sanger Sequencing for Detection of Low-frequency Somatic Mutation

Wild-type Blocking PCR Combined with Sanger Sequencing for Detection of Low-frequency Somatic Mutation

Published on: August 23, 2024

Analysis of the impact of ITMIG on clinical practice guidelines.

Main Results:

ITMIG has successfully organized individual efforts, enabling data collation and global collaboration.
Significant infrastructure has been established to support future research.
ITMIG's work supports the development of more robust, evidence-based guidelines.

Conclusions:

ITMIG has been instrumental in advancing the study of thymic malignancies.
The group provides a crucial foundation for developing evidence-based clinical practice guidelines.
Future progress in treating thymic tumors will benefit from ITMIG's collaborative framework.