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Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
X-ray Crystallography02:18

X-ray Crystallography

The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

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Updated: May 11, 2026

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

A simplified approach to quantitative coded aperture X-ray phase imaging.

Peter R T Munro1, Charlotte K Hagen, Magdalena B Szafraniec

  • 1Optical + Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia. peter.munro@uwa.edu.au

Optics Express
|May 15, 2013
PubMed
Summary

This study presents a new quantitative X-ray phase contrast imaging method using coded apertures. It works without knowing system parameters or needing perfectly absorbing apertures, simplifying imaging.

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Area of Science:

  • Physics
  • Medical Imaging
  • Materials Science

Background:

  • Quantitative X-ray phase contrast imaging (QPIC) is valuable for material and biological sample analysis.
  • Previous QPIC methods using coded apertures required precise knowledge of system parameters and ideal aperture properties.

Purpose of the Study:

  • To develop a QPIC method that does not require prior knowledge of system parameters.
  • To enable QPIC with partially absorbing apertures, enhancing practical applicability.

Main Methods:

  • A novel coded aperture technique for X-ray phase contrast imaging was developed.
  • The method was validated by performing quantitative imaging without knowledge of source size or element distances.
  • The approach accommodates apertures with partial absorption.

Main Results:

  • Successful quantitative X-ray phase imaging was achieved without needing to know individual system parameters.
  • The technique demonstrated robustness with partially absorbing apertures.
  • The developed method shows analogy to analyser-based imaging techniques.

Conclusions:

  • This work significantly simplifies the implementation of quantitative X-ray phase contrast imaging.
  • The findings broaden the applicability of coded aperture techniques in laboratory-based X-ray imaging.
  • The method offers a more practical and accessible approach to QPIC.