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Published on: May 31, 2013
5S rRNA: Structure and Function from Head to Toe
Olga A Dontsova1, Jonathan D Dinman
1Department of Chemistry, Moscow State University, Building A, Room 608, Vorobievy Gory, Moscow, Russia;
Abstract:
5S rRNA is uniquely positioned so as to link together all of the functional centers of the ribosome. Previous studies have supported the hypothesis that 5S rRNA acts as a physical transducer of information, facilitating communication between the different functional centers and coordinating of the multiple events catalyzed by the ribosome. Here, we present a synthesis of both structural and genetic information to construct a more detailed picture of how 5S rRNA may act to transmit and coordinate all of the functional centers of the ribosome.
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