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Updated: May 11, 2026

A High-throughput Assay to Assess and Quantify Neutrophil Extracellular Trap Formation
Published on: January 29, 2019
Systemic vasculitis associated with anti-neutrophil cytoplasmic antibodies against bactericidal/permeability
Atsuro Fukuhara1, Yoshinori Tanino, Suguru Sato
1Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, Japan.
Abstract:
Myeloperoxidase- and proteinase 3-anti-neutrophil cytoplasmic antibodies (ANCAs) are often negative in cases in which systemic vasculitis is highly suspected. We herein present a case of bactericidal/permeability increasing protein (BPI)-ANCA-positive systemic vasculitis. This case highlights the possible role of BPI-ANCA in the pathogenesis of systemic vasculitis as well as the possible use of BPI as a diagnostic tool. The accumulation of further case-based reports is expected to shed some light on the pathogesis of systemic vasculitis.
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