Infective endocarditis caused by Enterococcus faecalis treated with continuous infusion of ampicillin without

Taku Ogawa1, Masatoshi Sato, Shinsuke Yonekawa

  • 1Center for Infectious Diseases, Nara Medical University, Japan. t_ogawa@naramed-u.ac.jp

Insights

This study presents a successful case of infective endocarditis treatment using ampicillin monotherapy. Continuous ampicillin infusion achieved effective serum concentrations, offering an alternative to aminoglycosides and their associated toxicities.

Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Cardiology

Background:

  • Infective endocarditis is a serious infection often treated with aminoglycosides.
  • Aminoglycosides carry risks of nephrotoxicity and ototoxicity.
  • Enterococcus faecalis is a common pathogen in infective endocarditis.

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