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[Parvovirus B19 arthritis: Report of three cases]

María Ángela Carreño1, Eduardo Wainstein, Patricia Abumohor

  • 1Clínica Las Condes, Santiago, Chile. mcarreno@clc.cl

Revista Medica De Chile
|May 17, 2013
PubMed

Insights

Parvovirus B19 infection can cause significant joint pain and skin rashes in adults. Prompt diagnosis and anti-inflammatory treatment are key for managing symptoms and recovery.

Area of Science:

  • Infectious Diseases
  • Rheumatology
  • Dermatology

Background:

  • Parvovirus B19 is a common cause of illness, particularly in children, often presenting as a facial rash.
  • In adults, Parvovirus B19 infection frequently manifests with acute polyarthritis and skin rashes.

Observation:

  • Reported are three adult cases of Parvovirus B19 infection.
  • Case 1: A 40-year-old female with fever, myalgias, painful joint swelling, functional limitation, and extremity rash, positive for IgM antibodies, with skin biopsy showing leukocytoclastic vasculitis.
  • Case 2: A 40-year-old female with rash and hand/wrist pain, positive for IgM antibodies.
  • Case 3: A 38-year-old male with psoriasis experiencing progressive polyarthralgia, with high Parvovirus B19 viral load and positive IgM antibodies.

Findings:

  • All three patients tested positive for IgM antibodies against Parvovirus B19.
  • Leukocytoclastic vasculitis was observed in one patient's skin biopsy.
  • Viral load determination confirmed significant Parvovirus B19 presence in another patient.

Implications:

  • These cases highlight the diverse clinical presentations of Parvovirus B19 infection in adults, including significant rheumatological and dermatological symptoms.
  • Effective management strategies involve anti-inflammatory drugs, antihistamines, and acetaminophen.
  • Increased awareness of Parvovirus B19 as a cause of adult-onset arthritis and rash is crucial for timely diagnosis and treatment.

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