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[Collagenous colitis].

R Güller1

  • 1Gastroenterologische Praxis, Wettingen.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|June 26, 1990
PubMed
Summary

Collagenous colitis is a rare diarrheal disease characterized by a thickened collagen layer in the colon. Diagnosis requires biopsies from normal-appearing mucosa, with symptomatic treatment being the usual approach.

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[Colonic preparation with sodium phosphate. Prospective, randomized, placebo-controlled double blind study with various antiemetics].

Schweizerische medizinische Wochenschrift·1996

Area of Science:

  • Gastroenterology
  • Pathology

Context:

  • Collagenous colitis is a rare condition first described in 1976.
  • Characterized by a thickened subepithelial collagen layer throughout the colon.

Purpose:

  • To summarize the features of collagenous colitis based on 24 patient cases and literature review.
  • To highlight diagnostic challenges and treatment approaches.

Summary:

  • Patients present with chronic watery diarrhea.
  • Standard laboratory tests, radiology, and colonoscopy typically yield normal results.
  • Diagnosis relies on biopsies revealing subepithelial collagen, often from endoscopically normal mucosa.

Impact:

  • Emphasizes the need for vigilant colonoscopic examination and biopsy for diagnosis.
  • Suggests that microscopic colitis might be an early manifestation of collagenous colitis.
  • Indicates that symptomatic treatment with antidiarrheal drugs is generally effective.