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Updated: May 11, 2026

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
Published on: October 31, 2013
Electrophoresis of a DNA coil near a nanopore
Payam Rowghanian1, Alexander Y Grosberg
1Department of Physics and Center for Soft Matter Research, New York University, 4 Washington Place, New York, New York 10003, USA. payam.rowghanian@physics.nyu.edu
Abstract:
Motivated by DNA electrophoresis near a nanopore, we consider the flow field around an "elongated jet," a long thin source which injects momentum into a liquid. This solution qualitatively describes the electro-osmotic flow around a long rigid polymer, where due to electrohydrodynamic coupling, the solvent receives momentum from the electric field. Based on the qualitative behavior of the elongated jet solution, we develop a coarse-grained scheme which reproduces the known theoretical results regarding the electrophoretic behavior of a long rigid polymer and a polymer coil in a uniform field, which we then exploit to analyze the electrophoresis of a polymer coil in the nonuniform field near a nanopore.
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