Related Experiment Video
Updated: May 11, 2026
06:45
Continuous Liquid-Liquid Extraction of Medium-Chain Fatty Acids from Fermentation Broth Using Hollow-Fiber Membranes
Published on: August 9, 2024
Recent development and applications of dispersive liquid-liquid microextraction.
1College of Pharmacy, Hebei University, Baoding, 071002, China. yanhy@hbu.edu.cn
Journal of Chromatography. A
|May 18, 2013
Summary
Dispersive liquid-liquid microextraction (DLLME) offers a simple, eco-friendly sample preparation method. This review highlights recent DLLME advancements and applications in environmental, food, and biological analyses.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Dispersive liquid-liquid microextraction (DLLME) is a widely adopted sample pretreatment technique.
- DLLME is recognized for its simplicity, cost-effectiveness, and environmental friendliness.
- Since its invention in 2006, DLLME has gained significant traction in separation science.
Purpose of the Study:
- To review recent advancements in Dispersive liquid-liquid microextraction (DLLME).
- To categorize DLLME modifications into new extraction solvents, disperser solvents, and combined techniques.
- To summarize recent applications of DLLME in environmental, food, and biological sample analyses.
Main Methods:
- Exploration of novel extraction solvents for DLLME.
- Investigation of alternative disperser solvents to enhance DLLME efficiency.
- Integration of DLLME with other separation techniques to overcome limitations.
Main Results:
- DLLME modifications focus on improving extraction efficiency and expanding applicability.
- Recent studies demonstrate successful DLLME implementation across diverse sample matrices.
- The technique shows high enrichment factors due to a wide phase gap.
Conclusions:
- DLLME continues to evolve with innovative modifications and solvent choices.
- DLLME is a versatile technique with broad applications in various analytical fields.
- Future trends suggest further refinement and expanded use of DLLME in sample preparation.
Related Concept Videos
01:30Capillary Electrophoresis: Applications
Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
01:05High-Performance Liquid Chromatography: Elution Process
In High-Performance Liquid Chromatography (HPLC), the elution process is critical to the separation of analytes and the quality of chromatographic results. Elution describes how compounds move through the column and separate based on their interactions with the mobile and stationary phases. This process determines the resolution, peak shape, and retention times in the chromatogram, which are essential for identifying and quantifying components in complex mixtures. Understanding the elution...
00:56Extraction: Advanced Methods
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is formed in...
01:14Extraction: Partition and Distribution Coefficients
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an organic...
For extracting a solute from an aqueous phase into an organic...